Neratinib is effective in breast tumors bearing both amplification and mutation of ERBB2 (HER2) | Science Signaling
Mechanisms Underlying Recurrent Genomic Amplification in Human Cancers: Trends in Cancer
Trastuzumab — Mechanism of Action and Use in Clinical Practice | NEJM
Prognostic Value of Plasma HER2 Gene Copy Number in HER2-Positive Meta | OTT
Loss of HER2 in breast cancer: biological mechanisms and technical pitfalls
Frontiers | HER2 Low, Ultra-low, and Novel Complementary Biomarkers: Expanding the Spectrum of HER2 Positivity in Breast Cancer
HER2 signaling pathway, mechanism of action of targeted therapies, and... | Download Scientific Diagram
In HER2 gene-amplified breast carcinoma cells primarily responsive to... | Download Scientific Diagram
Palindromic amplification of the ERBB2 oncogene in primary HER2-positive breast tumors | Scientific Reports
Evolving novel anti-HER2 strategies - The Lancet Oncology
A common copy-number breakpoint of ERBB2 amplification in breast cancer colocalizes with a complex block of segmental duplications | Breast Cancer Research | Full Text
Mechanisms of resistance and sensitivity to anti-HER2 therapies in HER2+ breast cancer | Oncotarget
Automated detection of the HER2 gene amplification status in Fluorescence in situ hybridization images for the diagnostics of cancer tissues | Scientific Reports
Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer - ScienceDirect
Cancers | Free Full-Text | Emerging Role of ERBB2 in Targeted Therapy for Metastatic Colorectal Cancer: Signaling Pathways to Therapeutic Strategies
Mechanisms of neratinib resistance in HER2 -mutant metastatic breast cancer
General mechanisms of resistance to trastuzumab: presence of... | Download Scientific Diagram
Human Epidermal Growth Factor Receptor 2 (HER2) in Cancers: Overexpression and Therapeutic Implications
Chromosome 17 polysomy versus CEP17 gain/amplification. Possible... | Download Scientific Diagram
Evolving concepts in HER2 evaluation in breast cancer: Heterogeneity, HER2-low carcinomas and beyond - ScienceDirect
A) Schematic comparison of gene amplification and polysomy. The ratio... | Download Scientific Diagram
Molecular Mechanisms of Trastuzumab Resistance in HER2 Overexpressing Breast Cancer
HER2 Amplification or Overexpression in Upper GI Tract and Breast Cancer with Clinical Diagnosis and Treatment | IntechOpen
Introduction The effects of HER2 gene and receptor over- expression on breast cancer. Prognosis and treatment of HER2+ breast cancer. (See figure 1) - ppt download
